Description

3-Hydroxy-3-Phenylazetidine Trifluoroacetate is a high-purity, advanced pharmaceutical intermediate and building block. This compound is valued for its unique azetidine ring structure, which is a key scaffold in modern medicinal chemistry for developing novel therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric conditions.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• API Development: Serves as a key precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	3-Hydroxy-3-Phenylazetidine Trifluoroacetate
CAS No.	958297-39-7
Molecular Formula	C11H12F3NO3
Molecular Weight	263.21 g/mol
Synonyms	3-Phenyl-3-hydroxyazetidine trifluoroacetate; 3-Hydroxy-3-phenylazetidine TFA salt; 3-Phenylazetidin-3-ol trifluoroacetate; Azetidin-3-ol, 3-phenyl-, trifluoroacetate (1:1); TFA salt of 3-Hydroxy-3-phenylazetidine; 3-Phenyl-3-azetidinol trifluoroacetate; Building Block 958297-39-7
EINECS	Contact for details

Quality Control

Every batch of 3-Hydroxy-3-Phenylazetidine Trifluoroacetate is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment to guarantee it meets the stringent requirements for pharmaceutical R&D and process development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥98.0%
Purity (HPLC, Area%)	≥99.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.