Description

Desacetyl Cefathiamidine is a key pharmaceutical intermediate and metabolite of the antibiotic Cefathiamidine. This compound is of significant importance in the research, development, and quality control of advanced cephalosporin antibiotics. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in antibiotic synthesis, impurity profiling, and metabolic studies. The high-purity material ensures reliable results in analytical and process development applications.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of the antibiotic Cefathiamidine and related cephalosporin derivatives.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control testing in pharmaceutical laboratories.
• Impurity Profiling: Serves as a specified impurity or degradation product standard to monitor and control the quality of Cefathiamidine active pharmaceutical ingredient (API) and finished drug products.
• Metabolite Studies: Employed in pharmacokinetic and pharmacodynamic research to study the metabolism and biological activity of Cefathiamidine.
• Research & Development: Essential for academic and industrial R&D focused on novel antibiotic design, structure-activity relationship (SAR) studies, and biochemical pathways.

Basic Information

Item	Detail
Product Name	Desacetyl Cefathiamidine
CAS No.	958001-61-1
Molecular Formula	C17H21N5O5S2
Molecular Weight	463.51 g/mol
Synonyms	(6R,7R)-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Deacetylcefathiamidine; Desacetyl Cefathiamidin; Cefathiamidine Impurity; Cefathiamidine Related Compound A
EINECS	Contact for details

Quality Control

Our Desacetyl Cefathiamidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity assay, related substance analysis, and identity confirmation (IR, NMR) to ensure it meets stringent specifications for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every lot to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.