Description

3-(4-(Trifluoromethyl)Benzyl)Pyrrolidine is a high-value, fluorinated pyrrolidine derivative, serving as a crucial building block in advanced organic synthesis. Its core value lies in the unique combination of the pyrrolidine scaffold and the trifluoromethylbenzyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	3-(4-(Trifluoromethyl)Benzyl)Pyrrolidine
CAS No.	957998-84-4
Molecular Formula	C12H14F3N
Molecular Weight	229.24 g/mol
Synonyms	3-[(4-(Trifluoromethyl)phenyl)methyl]pyrrolidine; 1-[4-(Trifluoromethyl)benzyl]pyrrolidin-3-amine (tautomer); Pyrrolidine, 3-[[4-(trifluoromethyl)phenyl]methyl]-; 4-(Trifluoromethyl)benzylpyrrolidine; 3-(4-Trifluoromethyl-benzyl)-pyrrolidine; 3-(alpha,alpha,α-Trifluoro-p-tolyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 3-(4-(Trifluoromethyl)Benzyl)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.