Description

1-Difluoromethyl-3-Methyl-1H-Pyrazole-4-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in enabling the precise introduction of the difluoromethylpyrazole sulfonamide moiety, a key pharmacophore in modern agrochemical and pharmaceutical discovery. This compound is essential for research and development chemists in the crop protection and pharmaceutical industries, where it is used to create novel active ingredients with optimized properties.

Application

• Agrochemical Intermediate: A key precursor for synthesizing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluoromethylpyrazole scaffold.
• Pharmaceutical Building Block: Used in medicinal chemistry to develop potential drug candidates, particularly in areas requiring sulfonamide-based enzyme inhibitors.
• Chemical Research & Development: Serves as a versatile reagent for constructing complex heterocyclic compounds in academic and industrial R&D settings.
• Material Science: Potential use in creating specialized polymers or functional materials with specific surface properties.

Basic Information

Product Name	1-Difluoromethyl-3-Methyl-1H-Pyrazole-4-Sulfonyl Chloride
CAS No.	957490-44-7
Molecular Formula	C6H5ClF2N2O2S
Molecular Weight	238.63 g/mol
Synonyms	3-Methyl-1-(difluoromethyl)-1H-pyrazole-4-sulfonyl chloride; 1H-Pyrazole-4-sulfonyl chloride, 1-(difluoromethyl)-3-methyl-; 1-(Difluoromethyl)-3-methyl-1H-pyrazole-4-sulfonyl chloride; 4-Sulfonyl chloride-1-difluoromethyl-3-methylpyrazole; DFMP-SCl; 957490-44-7 (CAS)
EINECS	Contact for details

Quality Control

Our production of 1-Difluoromethyl-3-Methyl-1H-Pyrazole-4-Sulfonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.