Description

4-Bromo-1-(4-Nitro-Benzyl)-1H-Pyrazole is a high-purity, functionalized pyrazole derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceuticals and agrochemicals, enabling the introduction of both bromo and nitrobenzyl functional groups. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting kinase inhibition and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic materials.
• Chemical Synthesis: A versatile building block for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other functional group transformations.
• Academic & Industrial R&D: Essential for medicinal chemistry programs and discovery research in both university and corporate settings.

Basic Information

Product Name	4-Bromo-1-(4-Nitro-Benzyl)-1H-Pyrazole
CAS No.	957488-04-9
Molecular Formula	C10H8BrN3O2
Molecular Weight	282.10 g/mol
Synonyms	4-Bromo-1-[(4-nitrophenyl)methyl]-1H-pyrazole; 1-(4-Nitrobenzyl)-4-bromo-1H-pyrazole; 4-Bromo-1-(4-nitrobenzyl)pyrazole; 4-Bromo-1-(p-nitrobenzyl)-1H-pyrazole; 957488-04-9; 4-Br-1-(4-NO2-Bn)-Pyrazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-(4-Nitro-Benzyl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical characteristics are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.