Description

4-Nitro-1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole CAS NO 957481-53-7 is a high-purity, functionalized pyrazole derivative characterized by its nitro and trifluoromethylbenzyl substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel active molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the creation of new chemical entities and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to introduce complex functionalities into target molecules.
• Material Science Research: Acts as a precursor for the synthesis of specialty polymers, ligands for catalysis, or organic electronic materials.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological systems and target engagement.

Basic Information

Item	Details
Product Name	4-Nitro-1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole
CAS No.	957481-53-7
Molecular Formula	C11H8F3N3O2
Molecular Weight	271.20 g/mol
Synonyms	4-Nitro-1-[(3-(trifluoromethyl)phenyl)methyl]-1H-pyrazole; 1-(3-(Trifluoromethyl)benzyl)-4-nitro-1H-pyrazole; 4-Nitro-1-(3-trifluoromethylbenzyl)pyrazole; 957481-53-7; α-(3-Trifluoromethylbenzyl)-4-nitropyrazole
EINECS	Contact for details

Quality Control

Our 4-Nitro-1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.