Description

5-Methyl-3-Nitro-1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole is a high-value, synthetically versatile heterocyclic compound featuring a nitro-substituted pyrazole core and a trifluoromethyl benzyl group. This specific molecular architecture makes it a critical pharmaceutical intermediate and a valuable building block in advanced organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a core scaffold for developing new generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the nitro-pyrazole moiety.
• Chemical Synthesis Building Block: Used in medicinal chemistry and material science for constructing complex molecules, where the trifluoromethyl group can enhance metabolic stability and lipophilicity.
• Life Science Research: Employed in biochemical and pharmacological research as a standard or probe molecule for studying enzyme inhibition and receptor binding.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized dyes and functional pigments due to its nitro-aromatic structure.

Basic Information

Item	Details
Product Name	5-Methyl-3-Nitro-1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole
CAS No.	957400-33-8
Molecular Formula	C12H10F3N3O2
Molecular Weight	285.22 g/mol
Synonyms	1-[(3-Trifluoromethyl)phenyl]methyl]-5-methyl-3-nitro-1H-pyrazole; 3-Nitro-5-methyl-1-[(3-trifluoromethyl)benzyl]pyrazole; 5-Methyl-3-nitro-1-[(3-(trifluoromethyl)phenyl)methyl]-1H-pyrazole; 1-(3-Trifluoromethylbenzyl)-5-methyl-3-nitro-1H-pyrazole; 957400-33-8; 5-Methyl-3-nitro-1-(3-trifluoromethylbenzyl)pyrazole
EINECS	Contact for details

Quality Control

Our 5-Methyl-3-Nitro-1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or otherwise opaque.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.