Description

1-(2-Fluoro-Benzyl)-3-Nitro-1H-Pyrazole is a high-purity, fluorinated pyrazole derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and agrochemical building block, enabling the development of novel active ingredients. It is essential for R&D chemists and process development scientists in the life sciences and crop protection industries seeking to introduce specific fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorobenzyl and nitro-pyrazole groups contribute to biological activity and metabolic stability.
• Chemical Research & Development: Serves as a versatile scaffold in organic synthesis for exploring new chemical spaces and developing proprietary compounds.
• Material Science Precursor: Potential intermediate in the synthesis of specialty chemicals, dyes, or functional materials requiring specific fluorinated aromatic systems.

Basic Information

Product Name	1-(2-Fluoro-Benzyl)-3-Nitro-1H-Pyrazole
CAS No.	957354-37-9
Molecular Formula	C10H8FN3O2
Molecular Weight	221.19 g/mol
Synonyms	1-[(2-Fluorophenyl)methyl]-3-nitro-1H-pyrazole; 3-Nitro-1-(2-fluorobenzyl)-1H-pyrazole; 1-(2-Fluorobenzyl)-3-nitropyrazole; 1H-Pyrazole, 1-[(2-fluorophenyl)methyl]-3-nitro-; 957354-37-9; 1-(2-Fluorobenzyl)-3-nitro-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-Benzyl)-3-Nitro-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.