Description

1-Difluoromethyl-5-Methyl-1H-Pyrazole-4-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced chemical synthesis. This compound is valued for its role in introducing the difluoromethylpyrazole sulfonamide moiety, a key pharmacophore in modern agrochemical and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Agrochemical Research: Building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Biology Probe Development: Used to create sulfonamide-based probes for studying enzyme function and protein interactions.
• Material Science: Intermediate for synthesizing specialized polymers and functional materials with unique surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules in multi-step syntheses.

Basic Information

Product Name	1-Difluoromethyl-5-Methyl-1H-Pyrazole-4-Sulfonyl Chloride
CAS No.	957284-65-0
Molecular Formula	C6H5ClF2N2O2S
Molecular Weight	238.63 g/mol
Synonyms	5-Methyl-1-(difluoromethyl)-1H-pyrazole-4-sulfonyl chloride; 1H-Pyrazole-4-sulfonyl chloride, 1-(difluoromethyl)-5-methyl-; 1-(Difluoromethyl)-5-methyl-1H-pyrazole-4-sulfonyl chloride; 4-Sulfonyl chloride-1-difluoromethyl-5-methylpyrazole; DFMP-SCl
EINECS	Contact for details

Quality Control

Our 1-Difluoromethyl-5-Methyl-1H-Pyrazole-4-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We employ advanced analytical techniques including HPLC, NMR, and GC-MS for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.