Description

2-Chloro-N-(1-Methyl-1H-Pyrazol-4-yl)acetamide (Salt data: Free) is a high-purity, versatile chemical intermediate featuring a reactive chloroacetamide group linked to a methylpyrazole moiety. This compound is critical for synthetic chemists requiring precise molecular scaffolds for constructing complex heterocyclic systems. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the pyrazole core for bioactivity.
• Chemical Biology & Proteomics: Serves as a precursor for activity-based probes (ABPs) or affinity tags due to its electrophilic chloroacetamide group.
• Material Science: Potential monomer or cross-linking agent in the creation of specialized polymers with unique thermal or chemical properties.
• Custom Synthesis & Contract Manufacturing: Essential for fine chemical suppliers offering bespoke synthesis services for client-specific molecular targets.

Basic Information

Product Name	2-Chloro-N-(1-Methyl-1H-Pyrazol-4-yl)acetamide (Salt data: Free)
CAS No.	957261-64-2
Molecular Formula	C7H10ClN3O
Molecular Weight	187.63 g/mol
Synonyms	2-Chloro-N-(1-methyl-1H-pyrazol-4-yl)acetamide; 2-Chloroacetamide, N-(1-methyl-1H-pyrazol-4-yl)-; 1-Methyl-1H-pyrazol-4-amine, N-(chloroacetyl)-; 4-Amino-1-methylpyrazole chloroacetamide; N-(1-Methyl-1H-pyrazol-4-yl)-2-chloroacetamide; 957261-64-2; Chloroacetamide pyrazole derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-N-(1-Methyl-1H-Pyrazol-4-yl)acetamide is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments, supporting your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.