Description

1H-Pyrazole-4-Methanol, 1-Phenyl-5-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block characterized by its pyrazole core, phenyl substituent, and trifluoromethyl group. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where the CF3 moiety is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the bioactivity of the pyrazole scaffold.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals due to its rigid aromatic structure.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.
• Organic Synthesis: A versatile reagent for constructing complex heterocyclic systems via further functionalization of the methanol group.

Basic Information

Product Name	1H-Pyrazole-4-Methanol, 1-Phenyl-5-(Trifluoromethyl)-
CAS No.	957205-65-1
Molecular Formula	C11H9F3N2O
Molecular Weight	242.20 g/mol
Synonyms	1-Phenyl-5-(trifluoromethyl)-1H-pyrazole-4-methanol; 1-Phenyl-5-(trifluoromethyl)-4-pyrazolylmethanol; 4-(Hydroxymethyl)-1-phenyl-5-(trifluoromethyl)pyrazole; 1-Phenyl-5-trifluoromethyl-1H-pyrazole-4-methanol; [1-Phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl]methanol; 5-(Trifluoromethyl)-1-phenyl-1H-pyrazole-4-methanol
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-4-Methanol, 1-Phenyl-5-(Trifluoromethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality ensures the material is suitable for demanding applications in pharmaceutical R&D and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.