Description

3-Fluoro-2-(4-Morpholino)Pyridine-4-Boronic Acid Pinacol Ester is a high-value, multifunctional boronic ester derivative, serving as a critical synthetic intermediate in modern organic and medicinal chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific fluorinated heterocyclic structures.
• Material Science Research: Precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) and liquid crystal displays (LCDs).
• Chemical Biology Probes: Enables the synthesis of tagged molecules for studying biological pathways and protein interactions.
• Catalyst Ligand Development: Serves as a starting material for synthesizing novel ligands used in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Fluoro-2-(4-Morpholino)Pyridine-4-Boronic Acid Pinacol Ester
CAS No.	957198-29-7
Molecular Formula	C15H20BFN2O3
Molecular Weight	306.14 g/mol
Synonyms	2-(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)morpholine; 3-Fluoro-2-morpholinopyridine-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-fluoro-2-morpholinopyridine; 2-Morpholino-3-fluoropyridine-4-boronic acid pinacol ester; 957198-29-7; 3-Fluoro-2-morpholino-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(4-Morpholino)Pyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 19F, 11B), and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.