Description

8-Bromo-6-Nitroimidazo[1,2-A]Pyridine, Hcl is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and anti-infective research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Oncology Drug Development: Serves as a core scaffold for developing potential kinase inhibitors and other targeted cancer therapies.
• Anti-infective Agent Synthesis: Employed in the research and development of new antibacterial or antifungal compounds.
• Chemical Biology Probes: Utilized in the creation of specialized probes for studying biological processes and target identification.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.

Basic Information

Product Name	8-Bromo-6-Nitroimidazo[1,2-A]Pyridine, Hcl
CAS No.	957120-43-3
Molecular Formula	C7H5BrN4O2 • HCl
Molecular Weight	308.50 g/mol (Free base: 272.04 g/mol)
Synonyms	8-Bromo-6-nitroimidazo[1,2-a]pyridine hydrochloride; Imidazo[1,2-a]pyridine, 8-bromo-6-nitro-, hydrochloride; 8-Bromo-6-nitro-imidazo[1,2-a]pyridine HCl; 957120-43-3 (CAS); 8-Br-6-NO2-Imidazopyridine HCl; 8-Bromo-6-nitroimidazo[1,2-a]pyridine HCl salt
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Nitroimidazo[1,2-A]Pyridine, Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.