Description

3-Borono-5-Bromo-4-Fluorotoluene is a high-value, multi-functionalized aromatic boronic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and versatile building block in modern synthetic chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a key boronic acid reagent for forming carbon-carbon bonds in the synthesis of complex biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: For the research and development of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: As a building block for novel herbicides, fungicides, and insecticides that require specific halogen and fluorine substitution patterns.
• Ligand and Catalyst Development: In the creation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: For synthesizing organic electronic materials, such as monomers for conductive polymers or organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Used in the development of molecular probes and tags for bio-conjugation and imaging applications.

Basic Information

Product Name	3-Borono-5-Bromo-4-Fluorotoluene
CAS No.	957066-00-1
Molecular Formula	C7H6BBrFO2
Molecular Weight	230.84 g/mol
Synonyms	2-Bromo-6-Fluoro-3-Methylphenylboronic Acid; (2-Bromo-6-fluoro-3-methylphenyl)boronic acid; 5-Bromo-4-fluoro-3-methylbenzeneboronic acid; 3-Methyl-5-bromo-4-fluorobenzeneboronic acid; Boronic acid, B-(2-bromo-6-fluoro-3-methylphenyl)-; Toluene, 3-borono-5-bromo-4-fluoro-; 957066-00-1; BRN 9086975
EINECS	Contact for details

Quality Control

Our 3-Borono-5-Bromo-4-Fluorotoluene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.