Description

2,6-Difluoro-4-Hydroxybenzeneboronic Acid is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, where the boronic acid group enables efficient cross-coupling reactions, and the fluorine and hydroxyl substituents allow for precise tuning of molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex molecules, active pharmaceutical ingredients (APIs), and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially fluorinated bioactive compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent for constructing complex aromatic and heteroaromatic structures in academic and industrial R&D laboratories.
• Diagnostic Reagent Manufacturing: Employed in the synthesis of probes and sensors used in biochemical assays and diagnostic kits.

Basic Information

Product Name	2,6-Difluoro-4-Hydroxybenzeneboronic Acid
CAS No.	957065-87-1
Molecular Formula	C6H5BF2O3
Molecular Weight	173.92 g/mol
Synonyms	4-Hydroxy-2,6-difluorobenzeneboronic Acid; (4-Hydroxy-2,6-difluorophenyl)boronic Acid; 2,6-Difluoro-4-hydroxybenzeneboronic acid pinacol ester (common derivative); 2,6-DF-4-HO-PhB(OH)2; 957065-87-1; Boronic acid, B-(4-hydroxy-2,6-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our production of 2,6-Difluoro-4-Hydroxybenzeneboronic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment. We support compliance with global regulatory frameworks, including REACH and ICH guidelines, for research and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.