Description

2,6-Difluoro-3-Hydroxybenzeneboronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its unique molecular structure, featuring both boronic acid and phenolic hydroxyl functional groups, which enables precise cross-coupling reactions for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced materials through Suzuki-Miyaura coupling.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in creating complex biaryl structures found in many modern therapeutics.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, leveraging its fluorine atoms for enhanced biological activity and stability.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers where precise molecular architecture is required.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid coupling partner with aryl halides or triflates to form carbon-carbon bonds under palladium catalysis.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and sensors due to its ability to form reversible complexes with diols and other functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity boronic acid reagents.

Basic Information

Item	Details
Product Name	2,6-Difluoro-3-Hydroxybenzeneboronic Acid
CAS No.	957065-86-0
Molecular Formula	C6H5BF2O3
Molecular Weight	173.92 g/mol
Synonyms	2,6-Difluoro-3-hydroxybenzeneboronic acid; (2,6-Difluoro-3-hydroxyphenyl)boronic acid; 3-Borono-2,6-difluorophenol; Benzeneboronic acid, 2,6-difluoro-3-hydroxy-; 2,6-Difluoro-3-hydroxy phenylboronic acid; 957065-86-0; Boronic acid, B-(2,6-difluoro-3-hydroxyphenyl)-
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Hydroxybenzeneboronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and moisture absorption. Store away from incompatible materials such as strong oxidising agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.