Description

5-Fluoro-2-(Methylcarbamoyl)Phenylboronic Acid is a high-value boronic acid derivative and a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those containing fluorinated biphenyl or heterobiaryl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a highly effective organoboron reagent for palladium-catalyzed carbon-carbon bond formation with aryl halides.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with enhanced properties.
• Material Science: Employed in the creation of advanced organic electronic materials, such as OLEDs and organic semiconductors.
• Chemical Biology: Utilized as a probe or building block in the synthesis of molecules for biological target identification and validation.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	5-Fluoro-2-(Methylcarbamoyl)Phenylboronic Acid
CAS No.	957062-96-3
Molecular Formula	C9H9BFNO3
Molecular Weight	196.98 g/mol
Synonyms	2-Carbamoyl-4-fluorophenylboronic acid (Methylamide); (2-((Methylamino)carbonyl)-5-fluorophenyl)boronic acid; 5-Fluoro-2-(N-methylcarbamoyl)phenylboronic acid; 5-Fluoro-2-methylaminocarbonylphenylboronic acid; B-[2-[(Methylamino)carbonyl]-5-fluorophenyl]boronic acid; 957062-96-3; 5-Fluoro-N-methyl-2-boronobenzamide
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Methylcarbamoyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.