Description

2-(Ethoxycarbonyl)-5-Fluorophenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a protected carboxylic acid moiety, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in the synthesis of complex fluorinated molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorophenyl moiety enhances biological activity and stability.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boron reagent for forming carbon-carbon bonds to construct biaryl and heterobiaryl structures central to many drug candidates.
• Material Science Precursor: Employed in the creation of organic electronic materials, ligands for catalysts, and advanced polymers.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes and inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(Ethoxycarbonyl)-5-Fluorophenylboronic Acid
CAS No.	957062-87-2
Molecular Formula	C9H10BFO4
Molecular Weight	211.99 g/mol
Synonyms	5-Fluoro-2-(ethoxycarbonyl)phenylboronic Acid; (5-Fluoro-2-(ethoxycarbonyl)phenyl)boronic Acid; 2-Carbethoxy-5-fluorophenylboronic Acid; Ethyl 5-fluoro-2-boronobenzoate; 2-(Ethoxycarbonyl)-5-fluorobenzeneboronic Acid; B-[2-(Ethoxycarbonyl)-5-fluorophenyl]boronic Acid; CAS 957062-87-2
EINECS	Contact for details

Quality Control

Every batch of 2-(Ethoxycarbonyl)-5-Fluorophenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.