Description

4-(4-Boronophenoxy)-3-Nitrobenzotrifluoride is a high-value, multi-functional organic building block containing boronic acid, nitro, and trifluoromethyl functional groups. This compound is critical for facilitating complex cross-coupling reactions, particularly in the synthesis of advanced pharmaceutical intermediates and specialty materials. It is primarily sought after by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for creating biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging its boronic ester functionality.
• Material Science: Serves as a building block for synthesizing organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand & Catalyst Development: Employed in the creation of novel ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, fluorinated aromatic architectures.

Basic Information

Product Name	4-(4-Boronophenoxy)-3-Nitrobenzotrifluoride
CAS No.	957062-58-7
Molecular Formula	C₁₃H₉BF₃NO₄
Molecular Weight	311.02 g/mol
Synonyms	3-Nitro-4-(4-boronophenoxy)benzotrifluoride; 4-(4-Boronophenoxy)-3-nitro-α,α,α-trifluorotoluene; [4-(3-Nitro-4-trifluoromethylphenoxy)phenyl]boronic acid; 4-(3-Nitro-4-(trifluoromethyl)phenoxy)benzeneboronic acid; 4-(4-Boronophenyloxy)-3-nitrobenzotrifluoride; Boronic acid, B-[4-[[3-nitro-4-(trifluoromethyl)phenyl]oxy]phenyl]-; 957062-58-7
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Boronophenoxy)-3-Nitrobenzotrifluoride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling chemistry. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC/NMR), identity, and impurity profile. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.