Description

2,3-Difluoro-6-Methoxyphenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules for advanced materials and pharmaceuticals. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in fluorinated compound libraries.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoro-methoxy substitution pattern can enhance biological activity and stability.
• Material Science Research: Serves as a precursor for creating functional organic molecules used in organic light-emitting diodes (OLEDs), liquid crystals, and other electronic materials.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological processes and diagnostics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scale-up projects.

Basic Information

Product Name	2,3-Difluoro-6-Methoxyphenylboronic Acid
CAS No.	957061-21-1
Molecular Formula	C7H7BF2O3
Molecular Weight	187.94 g/mol
Synonyms	(2,3-Difluoro-6-methoxyphenyl)boronic acid; 2,3-Difluoro-6-methoxybenzeneboronic acid; B-(2,3-Difluoro-6-methoxyphenyl)boronic acid; 2,3-Difluoro-6-methoxybenzeneboronic acid; 957061-21-1; Boronic acid, B-(2,3-difluoro-6-methoxyphenyl)-; 2,3-Difluoro-6-methoxy-phenylboronic acid
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-6-Methoxyphenylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production. We adhere to ISO 9001 quality management principles, and our analytical methods include HPLC, NMR, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.