Description

3-(Benzyloxy)-6-Bromo-2-Fluorophenylboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, enabling precise cross-coupling reactions to construct complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand Synthesis: Serves as a building block for creating sophisticated ligands used in catalysis and material science.
• Functional Material Development: Incorporated into the synthesis of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and process development.

Basic Information

Product Name	3-(Benzyloxy)-6-Bromo-2-Fluorophenylboronic Acid
CAS No.	957035-10-8
Molecular Formula	C₁₃H₁₁BBrFO₃
Molecular Weight	339.94 g/mol
Synonyms	6-Bromo-2-fluoro-3-(phenylmethoxy)benzeneboronic acid; (6-Bromo-2-fluoro-3-(benzyloxy)phenyl)boronic acid; 3-Benzyloxy-6-bromo-2-fluorobenzeneboronic acid; Boronic acid, B-[6-bromo-2-fluoro-3-(phenylmethoxy)phenyl]-; 957035-10-8; 3-(Benzyloxy)-6-bromo-2-fluorophenylboronic acid pinacol ester (common derivative).
EINECS	Contact for details

Quality Control

Our production of 3-(Benzyloxy)-6-Bromo-2-Fluorophenylboronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR (¹H, ¹³C, ¹⁹F, ¹¹B), and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.