Description

2-Borono-3-Bromo-6-Fluoroanisole is a high-value, multi-functionalized aromatic building block containing boron, bromine, and fluorine substituents. This compound is essential for advanced organic synthesis, particularly in cross-coupling reactions where its boronic acid functionality enables precise carbon-carbon bond formation. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct complex, fluorinated bioactive molecules for next-generation herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for developing advanced organic electronic materials, such as OLEDs and semiconductors, leveraging its halogen and boron functionalities.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organoboron reagents.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise, multi-halogenated boronic acid derivatives.

Basic Information

Product Name	2-Borono-3-Bromo-6-Fluoroanisole
CAS No.	957035-08-4
Molecular Formula	C7H7BBrFO3
Molecular Weight	247.85 g/mol
Synonyms	(3-Bromo-6-fluoro-2-methoxyphenyl)boronic acid; 2-Methoxy-3-bromo-6-fluorophenylboronic acid; 3-Bromo-6-fluoro-2-methoxybenzeneboronic acid; Boronic acid, B-(3-bromo-6-fluoro-2-methoxyphenyl)-; 957035-08-4; B-(3-Bromo-6-fluoro-2-methoxyphenyl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Borono-3-Bromo-6-Fluoroanisole is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.