Description

4-Borono-2-Bromo-5-Fluorobenzoic Acid is a high-value, multifunctional aromatic building block containing halogen and boronic acid functional groups. This compound is critical for facilitating complex cross-coupling reactions, such as the Suzuki-Miyaura reaction, enabling the efficient synthesis of novel chemical architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring complex biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen and boron functionalities for structural diversification.
• Material Science Research: Serves as a building block for creating organic electronic materials, liquid crystals, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds between aromatic rings.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	4-Borono-2-Bromo-5-Fluorobenzoic Acid
CAS No.	957034-89-8
Molecular Formula	C7H5BBrFO4
Molecular Weight	261.83 g/mol
Synonyms	2-Bromo-5-fluoro-4-boronobenzoic acid; 4-Borono-2-bromo-5-fluorobenzoic acid; 5-Fluoro-2-bromo-4-carboxyphenylboronic acid; (2-Bromo-5-fluoro-4-carboxyphenyl)boronic acid; Benzoic acid, 4-borono-2-bromo-5-fluoro-; BBR-FBA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-Borono-2-Bromo-5-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.