Description

n-Cyclopentyl 4-Borono-2-Fluorobenzamide is a high-purity, advanced pharmaceutical intermediate featuring a unique boronic acid and fluorinated aromatic structure. This compound is critical for medicinal chemistry research, particularly in the development of novel therapeutics via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for synthesizing targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, especially those requiring boronic ester/acid coupling partners.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile reagent for forming carbon-carbon bonds in the construction of biaryl structures, a common motif in active pharmaceutical ingredients (APIs).
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and lead optimization to create libraries of compounds for biological evaluation.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential new drugs.
• Chemical Biology Research: Can be utilized as a probe or precursor in the study of biochemical pathways and target engagement.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents with specific activity.

Basic Information

Product Name	n-Cyclopentyl 4-Borono-2-Fluorobenzamide
CAS No.	957034-70-7
Molecular Formula	C₁₂H₁₅BFNO₂
Molecular Weight	235.07 g/mol
Synonyms	4-Borono-2-fluoro-N-cyclopentylbenzamide; 2-Fluoro-4-borono-N-cyclopentylbenzamide; 4-Carbamoyl-3-fluorophenylboronic acid, N-cyclopentyl-; Benzamide, 4-borono-2-fluoro-N-cyclopentyl-; 957034-70-7; n-Cyclopentyl-4-borono-2-fluorobenzamide; 4-Borono-2-fluorobenzoic acid cyclopentylamide
EINECS	Contact for details

Quality Control

Every batch of n-Cyclopentyl 4-Borono-2-Fluorobenzamide is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive pharmaceutical R&D. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.