Description

2-Bromo-5-(Trifluoromethoxy)Phenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs), particularly those containing trifluoromethoxy and bromo substituents for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the boronic acid group facilitates the introduction of complex aromatic systems.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials, due to its electron-deficient aromatic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Bromo-5-(Trifluoromethoxy)Phenylboronic Acid
CAS No.	957034-55-8
Molecular Formula	C7H5BBrF3O3
Molecular Weight	284.83 g/mol
Synonyms	[2-Bromo-5-(trifluoromethoxy)phenyl]boronic acid; (2-Bromo-5-(trifluoromethoxy)phenyl)boronic acid; 2-Bromo-5-(trifluoromethoxy)benzeneboronic acid; B-[2-Bromo-5-(trifluoromethoxy)phenyl]boronic acid; 957034-55-8; Boronic acid, B-[2-bromo-5-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Trifluoromethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.