Description

(3S)-3-Amino-1-Methyl-2-Pyrrolidinone Hydrochloride is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. Its value lies in providing a stereochemically defined building block for the development of novel active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the production of advanced drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and antiviral drug discovery.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective chemical reactions to create enantiomerically pure compounds.
• Peptidomimetics Research: Serves as a constrained scaffold or building block in the design of peptide-like molecules with enhanced metabolic stability.
• Chemical Biology Probes: Employed in the synthesis of specialized molecules for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.

Basic Information

Product Name	(3S)-3-Amino-1-Methyl-2-Pyrrolidinone Hydrochloride
CAS No.	956109-55-0
Molecular Formula	C5H11N2O•HCl
Molecular Weight	150.62 g/mol
Synonyms	(3S)-3-Amino-1-methylpyrrolidin-2-one hydrochloride; (S)-3-Amino-1-methyl-2-pyrrolidinone hydrochloride; 1-Methyl-3(S)-amino-2-pyrrolidinone hydrochloride; 2-Pyrrolidinone, 3-amino-1-methyl-, hydrochloride, (3S)-; L-3-Amino-1-methyl-2-pyrrolidinone hydrochloride
EINECS	Contact for details

Quality Control

Our (3S)-3-Amino-1-Methyl-2-Pyrrolidinone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.