Description

5,6,7,8-Tetrahydro-2-Isopropylpyrido[4,3-D]Pyrimidine is a high-purity heterocyclic organic compound with the CAS number 954230-61-6, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in medicinal chemistry. Its value lies in its complex pyridopyrimidine core structure, which is essential for synthesizing novel bioactive molecules targeting various therapeutic areas. This compound is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing new drug candidates, particularly in oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Chemical Biology Probes: Serves as a core scaffold for developing selective probes to study enzyme function and cellular pathways.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under GMP conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical innovation from discovery to development.

Basic Information

Product Name	5,6,7,8-Tetrahydro-2-Isopropylpyrido[4,3-D]Pyrimidine
CAS No.	954230-61-6
Molecular Formula	C10H15N3
Molecular Weight	177.25 g/mol
Synonyms	2-Isopropyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; 2-(Propan-2-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; Tetrahydro-2-isopropylpyrido[4,3-d]pyrimidine; Pyrido[4,3-d]pyrimidine, 5,6,7,8-tetrahydro-2-(1-methylethyl)-; SCHEMBL2188307; AKOS040759232; ZINC000257444433; A1-00826
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-2-Isopropylpyrido[4,3-D]Pyrimidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with the standards required for pharmaceutical R&D and GMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.