Description

3-(3,5-Dimethoxyphenyl)-3-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}Propanoic Acid is a specialized, high-purity organic building block designed for advanced pharmaceutical and biochemical research. This compound serves as a critical intermediate in the synthesis of complex molecules, offering precise structural control for medicinal chemistry and peptide synthesis applications. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
• Peptide Synthesis: Used in Fmoc-based solid-phase peptide synthesis (SPPS) as a protected amino acid derivative for constructing complex peptide sequences.
• Chemical Biology Research: Employed as a molecular probe or linker in the development of chemical tools for studying biological pathways and protein interactions.
• Process Development: Serves as a critical raw material for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke organic compounds and fine chemicals for specialized client needs.
• Academic Research: Utilized in university and institutional laboratories for fundamental research in organic synthesis methodology and new reaction development.

Basic Information

Product Name	3-(3,5-Dimethoxyphenyl)-3-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}Propanoic Acid
CAS No.	954225-63-9
Molecular Formula	C26H25NO7
Molecular Weight	463.48 g/mol
Synonyms	Fmoc-3-(3,5-Dimethoxyphenyl)-β-alanine; Fmoc-3-(3,5-Dimethoxyphenyl)-β-homoalanine; 3-(3,5-Dimethoxyphenyl)-3-[(9H-fluoren-9-ylmethoxy)carbonylamino]propanoic acid; 3-[(Fmoc-amino)-3-(3,5-dimethoxyphenyl)]propionic acid; N-Fmoc-3-(3,5-dimethoxyphenyl)-β-alanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(3,5-dimethoxyphenyl)-β-alanine; 3-(3,5-Dimethoxyphenyl)-3-[(9-fluorenylmethoxycarbonyl)amino]propanoic acid
EINECS	Contact for details

Quality Control

Our 3-(3,5-Dimethoxyphenyl)-3-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}Propanoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.