Description

Fmoc-(R)-2-Amino-3-(4-Ethylphenyl)Propanoic Acid is a high-purity, non-natural amino acid derivative designed for advanced peptide synthesis. This compound is a critical building block for the solid-phase synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is essential for researchers and manufacturers in pharmaceutical development, particularly for creating therapeutic peptides, diagnostic agents, and biochemical tools. The product is supplied to meet the stringent requirements of R&D and cGMP production environments.

Application

• Pharmaceutical Peptide Synthesis: A key protected amino acid for the Fmoc solid-phase peptide synthesis (SPPS) of novel therapeutic peptides and APIs.
• Peptidomimetic Drug Discovery: Used to incorporate the (R)-2-amino-3-(4-ethylphenyl)propanoic acid scaffold into drug candidates to modulate bioactivity and stability.
• Bioconjugation and Probe Development: Serves as a building block for creating labeled peptides, affinity tags, and molecular imaging probes.
• Chemical Biology Research: Enables the study of protein-protein interactions and enzyme specificity through the introduction of non-natural amino acid residues.
• Library Synthesis for Screening: Used in combinatorial chemistry to generate diverse peptide libraries for high-throughput screening against biological targets.

Basic Information

Product Name	Fmoc-(R)-2-Amino-3-(4-Ethylphenyl)Propanoic Acid
CAS No.	953030-54-1
Molecular Formula	C26H25NO4
Molecular Weight	415.48 g/mol
Synonyms	Fmoc-D-4-Ethylphenylalanine; Fmoc-(R)-4-Ethyl-Phe-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-ethyl-D-phenylalanine; (R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-ethylphenyl)propanoic acid; Fmoc-D-4-Et-Phe-OH; Nα-Fmoc-4-ethyl-D-phenylalanine; Fmoc-4-Ethyl-D-Phe; BOC Sciences Brand Product BLD-072005
EINECS	Contact for details

Quality Control

Every batch of Fmoc-(R)-2-Amino-3-(4-Ethylphenyl)Propanoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed HPLC, NMR, and optical rotation data are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.