Description

1-Pyrrolidinecarboxylic Acid, 3-(Aminooxy)-, 1,1-Dimethylethyl Ester, (3S)- is a high-purity, chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly due to its protected aminooxy and carboxylic acid functionalities. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and for use in bioconjugation chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in protease inhibitor and other small molecule therapeutic classes.
• Bioconjugation Reagent: Used in the site-specific modification of proteins, peptides, and antibodies, enabling the creation of antibody-drug conjugates (ADCs) and other biopharmaceuticals.
• Agrochemical Synthesis: Serves as a building block for developing novel, high-efficacy pesticides and herbicides with specific chiral configurations.
• Peptidomimetic Chemistry: Employed in the design and synthesis of peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic chemistry research.

Basic Information

Product Name	1-Pyrrolidinecarboxylic Acid, 3-(Aminooxy)-, 1,1-Dimethylethyl Ester, (3S)-
CAS No.	952747-27-2
Molecular Formula	C9H18N2O3
Molecular Weight	202.25 g/mol
Synonyms	(3S)-3-(Aminooxy)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl (3S)-3-(aminooxy)pyrrolidine-1-carboxylate; Boc-O-NH2-L-Pro-OH (tert-butyl ester); (S)-3-(Aminooxy)pyrrolidine-1-carboxylic acid tert-butyl ester; (S)-N-Boc-3-aminooxypyrrolidine; 1-Pyrrolidinecarboxylic acid, 3-(aminooxy)-, 1,1-dimethylethyl ester, (3S)-; (S)-tert-Butyl 3-(aminooxy)pyrrolidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxylic Acid, 3-(Aminooxy)-, 1,1-Dimethylethyl Ester, (3S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.