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Methyl 6-Formyl-1-Methyl-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate CAS NO 952182-35-3


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CAS No.:952182-35-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 6-Formyl-1-Methyl-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolopyridine scaffold. This compound is of significant value for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including kinase inhibitors and other targeted small-molecule drugs.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for oncology and other therapeutic areas.
  • Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
  • Kinase Inhibitor Development: Used in the construction of heterocyclic cores for potential kinase inhibitors due to its privileged structure.
  • Chemical Synthesis: Employed in organic synthesis for the preparation of more complex fused heterocyclic systems.
  • Bioconjugation & Probe Synthesis: The formyl group provides a handle for bioconjugation chemistry, useful in creating molecular probes.

Basic Information

Item Detail
Product Name Methyl 6-Formyl-1-Methyl-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate
CAS No. 952182-35-3
Molecular Formula C12H10N2O3
Molecular Weight 230.22 g/mol
Synonyms 6-Formyl-1-methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid methyl ester; Methyl 1-methyl-6-formyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate; 1-Methyl-6-formyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid methyl ester; 952182-35-3; Pyrrolo[3,2-b]pyridine-2-carboxylate, methyl 6-formyl-1-methyl-1H-; CAS 952182-35-3
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Quality Control

Our Methyl 6-Formyl-1-Methyl-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to prevent degradation.

Specification

Item Specification
Appearance Off-white to light yellow powder
Identification (HPLC) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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