Description

2-Fluoro-3-Methoxytoluene (CAS NO 951885-64-6) is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both fluorine and methoxy substituents on a toluene backbone, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated aromatic cores in electronic materials, contributing to improved performance in display and lighting technologies.
• Organic Synthesis & Catalysis: Employed as a specialized reagent in cross-coupling reactions and as a ligand precursor in catalytic systems due to its unique electronic profile.
• Chemical Research & Development: Essential for academic and industrial R&D labs exploring structure-activity relationships (SAR) and new synthetic methodologies involving fluorinated arenes.

Basic Information

Product Name	2-Fluoro-3-Methoxytoluene
CAS No.	951885-64-6
Molecular Formula	C8H9FO
Molecular Weight	140.16 g/mol
Synonyms	1-Fluoro-2-methoxy-3-methylbenzene; 3-Methyl-2-fluoroanisole; 2-Fluoro-3-methylanisole; o-Fluoro-m-methylanisole; 2-Fluoro-3-methoxytoluene; Toluene, 2-fluoro-3-methoxy-; 3-Methoxy-2-fluorotoluene; 2-Fluoro-3-methylmethoxybenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Methoxytoluene is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flames. Incompatible with strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.