Description

1H-Pyrrole, 2,2-[[4-(Methyl-D3)Phenyl]Methylene]Bis- is a specialized deuterated pyrrole derivative, a high-value building block for advanced research and development. This compound is critical for applications requiring isotopic labeling, offering enhanced metabolic stability and traceability in analytical studies. It is primarily sought by pharmaceutical, agrochemical, and advanced material scientists for use in drug discovery, mechanistic studies, and the synthesis of novel organic electronic materials.

Application

• Pharmaceutical Research & Development: As a deuterated synthon for creating isotopically labeled drug candidates to study Absorption, Distribution, Metabolism, and Excretion (ADME) properties.
• Agrochemical Innovation: Used in the synthesis of deuterated active ingredients or intermediates to improve environmental persistence and study degradation pathways.
• Organic Electronics: Serves as a precursor for synthesizing novel conjugated polymers and small molecules for OLEDs, OFETs, and other optoelectronic devices.
• Analytical Chemistry: Employed as an internal standard in Mass Spectrometry (MS) and Nuclear Magnetic Resonance (NMR) for quantitative analysis due to its isotopic signature.
• Chemical Biology & Proteomics: Utilized in probe development for activity-based protein profiling (ABPP) and other bioorthogonal labeling strategies.
• Material Science Research: A key intermediate for developing functional dyes, pigments, and advanced polymeric materials with tailored properties.

Basic Information

Product Name	1H-Pyrrole, 2,2-[[4-(Methyl-D3)Phenyl]Methylene]Bis-
CAS No.	950836-06-3
Molecular Formula	C19H14D3N
Molecular Weight	262.36 g/mol
Synonyms	Bis(2,2-dimethyl-1H-pyrrol-1-yl)[4-(trideuteriomethyl)phenyl]methane; 2,2'-((4-(Methyl-d3)phenyl)methylene)bis(1H-pyrrole); Deuterated Pyrrole Derivative; 4-(Trideuteriomethyl)benzylidene bis(2,2-dimethylpyrrole); 950836-06-3
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced and controlled under a strict quality management system to ensure batch-to-batch consistency and high isotopic purity. Each batch of 1H-Pyrrole, 2,2-[[4-(Methyl-D3)Phenyl]Methylene]Bis- is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity (by HPLC/GC), isotopic enrichment (by 1H/2H NMR or MS), and identity confirmation. We support cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a desiccated environment to prevent moisture absorption, which may affect stability and performance. Handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to ensure optimal shelf life.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.