Description

2-Chloro-n-(8-Nitro-3,4-Dihydro-2H-1,5-Benzodioxepin-7-Yl)Acetamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzodioxepin core structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel therapeutic agents targeting complex biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with benzodioxepin-based structures for potential CNS or anti-inflammatory applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.
• Academic Research: Employed in university and institutional laboratories for studying heterocyclic chemistry and developing new synthetic methodologies.
• Preclinical Development: Serves as a precursor for generating compounds used in pharmacological screening and early-stage toxicology studies.

Basic Information

Product Name	2-Chloro-n-(8-Nitro-3,4-Dihydro-2H-1,5-Benzodioxepin-7-Yl)Acetamide
CAS No.	949984-49-0
Molecular Formula	C13H13ClN2O5
Molecular Weight	312.71 g/mol
Synonyms	2-Chloro-N-(8-nitro-3,4-dihydro-2H-1,5-benzodioxepin-7-yl)acetamide; 7-[(2-Chloroacetyl)amino]-8-nitro-2,3-dihydro-1,5-benzodioxepin; 949984-49-0; 2-Chloroacetamide, N-(8-nitro-3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-; 8-Nitro-3,4-dihydro-2H-1,5-benzodioxepin-7-amine, N-(2-chloroacetyl)-; Benzodioxepin acetamide derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-(8-Nitro-3,4-Dihydro-2H-1,5-Benzodioxepin-7-Yl)Acetamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ISO 9001 quality management standards, and production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in amber glass or opaque packaging to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.