Description

2-Chloro-N-[2-(trifluoromethyl)phenyl]propanamide is a specialized organic compound featuring a chloro-substituted propanamide backbone linked to a trifluoromethylphenyl group. This unique molecular architecture makes it a valuable building block and intermediate in advanced chemical synthesis, particularly where the introduction of fluorine and chlorine atoms is required to modulate the properties of target molecules. It is primarily utilized by pharmaceutical, agrochemical, and advanced material research sectors for developing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological or metabolic disorders.
• Agrochemical Research: Serves as a critical building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science: Used in the research and development of specialty polymers and liquid crystals, where its structure can influence thermal stability and optical properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex organic molecules, particularly in amide bond formation and aryl functionalization reactions.
• Fluorochemical Production: Acts as an intermediate in the manufacture of more complex fluorinated compounds used in various high-performance applications.

Basic Information

Product Name	2-Chloro-N-[2-(trifluoromethyl)phenyl]propanamide
CAS No.	949444-74-0
Molecular Formula	C10H9ClF3NO
Molecular Weight	251.63 g/mol
Synonyms	2-Chloro-N-[2-(trifluoromethyl)phenyl]propanamide; Propanamide, 2-chloro-N-[2-(trifluoromethyl)phenyl]-; α-Chloro-2'-(trifluoromethyl)propionanilide; 2-Chloro-N-(2-trifluoromethylphenyl)propionamide; N-(2-Trifluoromethylphenyl)-2-chloropropanamide; 949444-74-0; CAS 949444-74-0
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-[2-(trifluoromethyl)phenyl]propanamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.