Description

n-Formyl-L-Glutamic Acid is a chemically modified derivative of the amino acid L-glutamic acid, where a formyl group protects the α-amino functionality. This compound is valued as a key chiral building block and protected intermediate in the synthesis of complex peptides, pharmaceuticals, and fine chemicals. It is primarily utilized by research institutions, pharmaceutical development laboratories, and manufacturers of high-purity active pharmaceutical ingredients (APIs) and specialty biochemicals.

Application

• Pharmaceutical Intermediate: A crucial protected precursor in the multi-step synthesis of peptide-based drugs and other bioactive molecules.
• Biochemical Research: Used as a reagent in enzymatic studies and metabolic pathway research involving glutamic acid derivatives.
• Peptide Synthesis: Serves as a building block in solid-phase and solution-phase peptide synthesis, where the formyl group provides selective protection.
• Fine Chemical Production: Employed in the manufacture of specialized chiral compounds for agrochemicals and advanced materials.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	n-Formyl-L-Glutamic Acid
CAS No.	1681-96-5
Molecular Formula	C6H9NO5
Molecular Weight	175.14 g/mol
Synonyms	N-Formyl-L-glutamic acid; (S)-2-Formamidopentanedioic acid; L-Glutamic acid, N-formyl-; Formylglutamic acid; FGA; NSC 33431; H-L-Glu(For)-OH; N-Formylglutamic acid
EINECS	Contact for details

Quality Control

Our n-Formyl-L-Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling, to ensure it meets stringent specifications for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	+14.0° to +18.0° (c=1 in H₂O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.