Description

Boc-Cys(Me)-Oh CAS NO 16947-80-1 is a protected derivative of the amino acid cysteine, specifically featuring a tert-butoxycarbonyl (Boc) protecting group on the amine and a methyl group on the sulfur atom. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of a modified cysteine residue while preventing unwanted side reactions. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who are developing peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Peptide Synthesis: A key intermediate in the solid-phase and solution-phase synthesis of complex peptides and proteins.
• Pharmaceutical Research: Used in the development of peptide drugs, hormone analogs, and other bioactive compounds where cysteine modification is required.
• Bioconjugation: Serves as a precursor for creating thioether linkages or other site-specific modifications in antibody-drug conjugates (ADCs) and protein engineering.
• Chemical Biology: Employed in the study of protein structure, function, and folding, as well as in the design of enzyme inhibitors.
• Material Science: Can be used to synthesize functionalized polymers and biomaterials with specific thiol-reactive properties.

Basic Information

Product Name	Boc-Cys(Me)-Oh
CAS No.	16947-80-1
Molecular Formula	C9H17NO4S
Molecular Weight	235.30 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-S-methyl-L-cysteine; Boc-S-methyl-L-cysteine; (2R)-2-[(tert-Butoxycarbonyl)amino]-3-(methylsulfanyl)propanoic acid; Boc-Cys(Me)-OH; Boc-L-Cys(Me)-OH; N-Boc-S-methylcysteine; L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; Boc-Cysteine(S-Me)-OH
EINECS	Contact for details

Quality Control

Our Boc-Cys(Me)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for peptide synthesis intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.2%
Chiral Purity (HPLC)	≥99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.