Description

(R)-(-)-2-Amino-1-Butanol CAS NO 5856-63-3 is a high-purity chiral amino alcohol, serving as a critical building block in asymmetric synthesis and pharmaceutical manufacturing. Its enantiomeric purity is essential for producing active pharmaceutical ingredients (APIs) with the desired stereochemistry and biological activity. This compound is primarily needed by research institutions, fine chemical producers, and pharmaceutical companies engaged in the development of chiral drugs, agrochemicals, and specialty catalysts.

Application

• Chiral Auxiliary and Resolving Agent: Used in the resolution of racemic mixtures and as a chiral auxiliary in asymmetric synthesis.
• Pharmaceutical Intermediate: A key precursor in the synthesis of enantiomerically pure drugs, particularly β-blockers and other cardiovascular agents.
• Catalyst Ligand Synthesis: Employed in the preparation of chiral ligands for metal-catalyzed reactions, such as hydrogenation and cross-coupling.
• Agrochemical Production: Used in the manufacture of chiral pesticides and herbicides where specific stereochemistry is required for efficacy.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and chiral compounds.
• Fine Chemical Synthesis: Serves as a building block for complex natural products, flavors, and fragrances requiring chiral centers.

Basic Information

Product Name	(R)-(-)-2-Amino-1-Butanol
CAS No.	5856-63-3
Molecular Formula	C4H11NO
Molecular Weight	89.14 g/mol
Synonyms	(R)-2-Amino-1-butanol; (R)-(-)-2-Aminobutanol; D-(-)-2-Amino-1-butanol; (2R)-2-Aminobutan-1-ol; (R)-1-Hydroxy-2-aminobutane; (R)-2-Aminobutyl alcohol; (R)-2-AB; (R)-Butanol, 2-amino-
EINECS	227-483-6

Quality Control

Our (R)-(-)-2-Amino-1-Butanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing specific results for enantiomeric excess (ee), chemical purity, and identity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Specific Rotation [α]20/D	-14.0° to -16.0° (c=1 in H2O)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.