Description

1,2-Difluoro-4-propoxybenzene is a high-purity fluorinated aromatic ether building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active ingredients, liquid crystals, and specialty materials where the introduction of fluorine and alkoxy groups is required to modulate biological activity, stability, and physical properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluorophenoxy moiety can enhance bioavailability and environmental stability.
• Liquid Crystal Materials: Serves as a core component or side-chain precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronics: Employed in the development of organic semiconductors, charge-transport materials, and electro-optical polymers due to its electron-withdrawing characteristics and structural rigidity.
• Chemical Research & Development: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution in academic and industrial R&D laboratories.
• Specialty Polymer Modification: Used to introduce fluorine and aromatic ether functionalities into polymer backbones to improve chemical resistance, thermal stability, and optical properties.

Basic Information

Product Name	1,2-Difluoro-4-propoxybenzene
CAS No.	949027-32-1
Molecular Formula	C9H10F2O
Molecular Weight	172.17 g/mol
Synonyms	4-Propoxy-1,2-difluorobenzene; 1,2-Difluoro-4-propoxybenzene; Benzene, 1,2-difluoro-4-propoxy-; 1,2-Difluoro-4-(propyloxy)benzene; 1,2-Difluoro-4-n-propoxybenzene; 3,4-Difluorophenyl propyl ether
EINECS	Contact for details

Quality Control

Our 1,2-Difluoro-4-propoxybenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.