Description

3-Trifluoromethoxy-Propan-1-Ol is a high-value fluorinated alcohol building block, distinguished by its trifluoromethoxy functional group which imparts unique electronic and steric properties. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
• Polymer Modification: Incorporated as a monomer or chain terminator to create specialty fluoropolymers with enhanced chemical resistance and surface properties.
• Organic Synthesis Reagent: Utilized as a versatile reagent in nucleophilic substitution and coupling reactions to introduce fluorinated alkoxy chains.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Trifluoromethoxy-Propan-1-Ol
CAS No.	949009-61-4
Molecular Formula	C₄H₇F₃O₂
Molecular Weight	144.09 g/mol
Synonyms	3-(Trifluoromethoxy)propan-1-ol; 3-(Trifluoromethoxy)-1-propanol; 1-Propanol, 3-(trifluoromethoxy)-; 3-Trifluoromethoxypropanol; 3-Oxy-1-propanol trifluoromethyl ether; Trifluoromethoxypropanol; TFMP; TFMOP
EINECS	Contact for details

Quality Control

Our 3-Trifluoromethoxy-Propan-1-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (20°C)	~1.25 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.