Description

Ethyl 2-Methyl-4,4,4-Trifluorobutyrate is a versatile fluorinated ester building block prized for its unique trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for synthetic chemists developing advanced materials and active pharmaceutical ingredients (APIs) where fluorine substitution is critical. It serves as a key intermediate in the agrochemical, pharmaceutical, and specialty chemical industries for the synthesis of complex fluoroorganic compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging the trifluoromethyl group to improve bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Specialty Polymer Modifier: Employed to introduce fluorine into polymer chains, enhancing material properties such as chemical resistance, thermal stability, and surface characteristics.
• Fluorinated Surfactant Precursor: Acts as a key intermediate in the synthesis of high-performance fluorosurfactants used in coatings, fire-fighting foams, and electronics.
• Organic Synthesis Reagent: Utilized in various organic transformations, including esterifications, alkylations, and as a source of the 2-methyl-4,4,4-trifluorobutyl moiety in complex molecule assembly.

Basic Information

Product Name	Ethyl 2-Methyl-4,4,4-Trifluorobutyrate
CAS No.	143484-00-8
Molecular Formula	C7H11F3O2
Molecular Weight	184.16 g/mol
Synonyms	Ethyl 2-Methyl-4,4,4-Trifluorobutanoate; 4,4,4-Trifluoro-2-methylbutyric Acid Ethyl Ester; 2-Methyl-4,4,4-Trifluorobutanoic Acid Ethyl Ester; Butanoic acid, 4,4,4-trifluoro-2-methyl-, ethyl ester; Ethyl α-Methyl-4,4,4-Trifluorobutyrate; Ethyl 4,4,4-Trifluoro-2-methylbutyrate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Methyl-4,4,4-Trifluorobutyrate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.3750 - 1.3850
Density (20°C)	1.15 - 1.25 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.