Description

(R)-2-[Bis(3,5-Dimethylphenyl)Methyl]Pyrrolidine is a high-purity chiral pyrrolidine derivative, a sophisticated building block prized for its role in asymmetric synthesis and catalysis. Its value lies in its ability to act as a chiral ligand or organocatalyst, enabling the production of enantiomerically pure compounds critical for advanced research and development. This compound is essential for pharmaceutical chemists and R&D teams in the life sciences sector, particularly those developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where stereochemical control is paramount.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation and cross-coupling.
• Utilized as an organocatalyst in enantioselective synthesis for constructing complex molecular architectures.
• A key synthetic intermediate in the research and development of novel pharmaceutical candidates and APIs.
• Employed in the synthesis of advanced agrochemicals requiring specific stereochemistry for enhanced activity.
• Used in academic and industrial research for methodological development in organic and medicinal chemistry.
• Serves as a building block for creating custom chiral auxiliaries and specialty catalysts.

Basic Information

Product Name	(R)-2-[Bis(3,5-Dimethylphenyl)Methyl]Pyrrolidine
CAS No.	948595-04-8
Molecular Formula	C21H27N
Molecular Weight	293.45 g/mol
Synonyms	(R)-2-[Bis(3,5-dimethylphenyl)methyl]pyrrolidine; (R)-2-(Bis(3,5-dimethylphenyl)methyl)pyrrolidine; (R)-2-[Di(3,5-xylyl)methyl]pyrrolidine; (R)-2-((3,5-Dimethylphenyl)(3,5-dimethylphenyl)methyl)pyrrolidine; (R)-2-(Bis(3,5-dimethylphenyl)methyl)-1-pyrroline (precursor); (R)-XYL-Pyrrolidine; Chiral Pyrrolidine Derivative 948595-04-8
EINECS	Contact for details

Quality Control

Our (R)-2-[Bis(3,5-Dimethylphenyl)Methyl]Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.