Description

(11Bs)-8,9,10,11,12,13,14,15-Octahydro-N,n-Bis[(1S)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine is a sophisticated chiral organophosphorus compound that serves as a high-value intermediate or ligand in advanced synthetic chemistry. Its complex, sterically hindered structure makes it a powerful tool for inducing enantioselectivity in catalytic reactions. This compound is primarily sought after by research institutions and pharmaceutical developers working on the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals where precise stereochemical control is paramount.

Application

• Asymmetric Catalysis: Employed as a chiral ligand or catalyst precursor in transition metal-catalyzed reactions, such as hydrogenation, hydroformylation, and cross-coupling.
• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders or requiring specific chiral centers.
• Methodology Development: Used in academic and industrial R&D to develop new enantioselective synthetic methodologies and protocols.
• Fine Chemical Synthesis: Facilitates the production of high-purity, single-enantiomer specialty chemicals for agrochemicals, flavors, and fragrances.
• Material Science Research: Investigated for potential use in creating chiral polymers or frameworks with unique optical or catalytic properties.

Basic Information

Product Name	(11Bs)-8,9,10,11,12,13,14,15-Octahydro-N,n-Bis[(1S)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine
CAS No.	948309-50-0
Molecular Formula	C38H38NO2P
Molecular Weight	571.69 g/mol
Synonyms	P-((1S)-1-Phenylethyl)-P'-((1S)-1-phenylethyl)-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; (S,S)-DACH-Phenyl Trost Ligand Derivative; Chiral Dinaphthodioxaphosphepinamine; (11bS)-4-Amino-8,9,10,11,12,13,14,15-octahydro-N,N-bis[(1S)-1-phenylethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin; Contact for additional aliases.
EINECS	Contact for details

Quality Control

Every batch of (11Bs)-8,9,10,11,12,13,14,15-Octahydro-N,n-Bis[(1S)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine is produced and analyzed under strict quality management protocols to ensure exceptional purity and enantiomeric excess (ee). Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing chiral purity (HPLC), assay, and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a dry, cool, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.