Description

(S)-2-Amino-4-Naphthalen-1-Yl-Butyric Acid is a chiral, non-proteinogenic amino acid derivative featuring a naphthyl side chain. This compound matters as a sophisticated building block in medicinal chemistry, enabling the synthesis of novel, biologically active molecules with enhanced target specificity. Pharmaceutical researchers and fine chemical manufacturers need it for the development of new drug candidates, particularly in areas like enzyme inhibition and receptor modulation.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Protease Inhibitor Synthesis: Used in constructing peptide-mimetic scaffolds for inhibitors targeting specific proteases.
• Chemical Biology Probes: Serves as a component in designing fluorescent or affinity-labeled probes for studying protein function.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective synthetic routes.
• Peptidomimetic Research: Integral for creating modified peptides with improved metabolic stability and bioavailability.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory medicinal chemistry projects.

Basic Information

Product Name	(S)-2-Amino-4-Naphthalen-1-Yl-Butyric Acid
CAS No.	948048-71-3
Molecular Formula	C₁₄H₁₅NO₂
Molecular Weight	229.27 g/mol
Synonyms	(S)-2-Amino-4-(naphthalen-1-yl)butanoic acid; (S)-2-Amino-4-(1-naphthyl)butyric acid; (S)-α-Amino-1-naphthalenebutanoic acid; (S)-Homo-1-naphthylalanine; (S)-1-Nal(4); (S)-4-(1-Naphthyl)-2-aminobutanoic acid; L-1-Naphthylhomoalanine
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-4-Naphthalen-1-Yl-Butyric Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.