Description

2-Cyano-3-(4-Fluorophenyl)Propionic Acid is a high-value fluorinated organic intermediate with a cyano functional group. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering a versatile handle for further chemical modifications. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic disorders.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Liquid Crystal Material Research: Used in the development of fluorinated components for advanced display technologies.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a starting material for electron-transport or emissive layer compounds.
• Peptidomimetics & Protease Inhibitors: The cyano and acid groups make it valuable for constructing enzyme inhibitor scaffolds in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of tailored compounds for client-specific projects.

Basic Information

Product Name	2-Cyano-3-(4-Fluorophenyl)Propionic Acid
CAS No.	948015-66-5
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	3-(4-Fluorophenyl)-2-cyanopropanoic Acid; (4-Fluorophenyl)cyanoacetic Acid Ethyl Ester derivative; 2-Cyano-3-(p-fluorophenyl)propanoic Acid; 4-Fluoro-α-cyanohydrocinnamic Acid; NSC 405122; p-Fluorophenyl-2-cyanopropionic Acid; β-Cyano-β-(4-fluorophenyl)propionic Acid
EINECS	Contact for details

Quality Control

Our 2-Cyano-3-(4-Fluorophenyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.