Description

Ethyl 3-(4-Fluorophenyl)-3-Oxopropanoate is a high-purity fluorinated β-ketoester building block essential for advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including potential central nervous system (CNS) agents and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Chemical Research & Development: Serves as a versatile building block for heterocyclic chemistry, enabling the construction of pyrazoles, isoxazoles, and other fused ring systems.
• Material Science Precursor: Employed in the synthesis of specialized monomers or ligands for advanced polymeric materials and catalysts.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	Ethyl 3-(4-Fluorophenyl)-3-Oxopropanoate
CAS No.	1999-00-4
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	Ethyl 4-Fluorobenzoylacetate; 4'-Fluorobenzoylacetic Acid Ethyl Ester; Ethyl (4-Fluorobenzoyl)acetate; 3-Oxo-3-(4-fluorophenyl)propanoic Acid Ethyl Ester; 1-Ethoxy-1-oxo-3-(4-fluorophenyl)propan-2-one; Ethyl 4-Fluorobenzoylacetonate; 4-Fluorophenyl 3-oxobutanoate; FBAE
EINECS	217-889-7

Quality Control

Our Ethyl 3-(4-Fluorophenyl)-3-Oxopropanoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical and agrochemical R&D. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.