Description

Difluoro-Propanedioicacid CAS NO 1514-85-8 is a specialized fluorinated dicarboxylic acid derivative, serving as a versatile and high-value building block in advanced chemical synthesis. Its unique structure, featuring two fluorine atoms, is critical for modulating the electronic properties, metabolic stability, and lipophilicity of target molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate fluorine motifs for enhanced product performance.

Application

• Pharmaceutical Intermediates: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitors and other small molecule drugs where fluorine substitution is desired.
• Agrochemical Synthesis: Used in the research and production of modern herbicides and pesticides, where the difluoro moiety can improve biological activity and environmental persistence profiles.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Advanced Material Precursors: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials requiring specific dielectric properties.
• Organic Synthesis Building Block: Utilized in various name reactions (e.g., Knoevenagel condensation) to create complex, fluorinated organic molecules for research purposes.

Basic Information

Item	Details
Product Name	Difluoro-Propanedioicacid
CAS No.	1514-85-8
Molecular Formula	C3H2F2O4
Molecular Weight	140.05 g/mol
Synonyms	2,2-Difluoromalonic Acid; Difluoromalonic Acid; Propanedioic Acid, 2,2-Difluoro-; 2,2-Difluoropropanedioic Acid; NSC 5111; AI3-28444; CCRIS 5986; HSDB 8170; EINECS 216-158-8
EINECS	216-158-8

Quality Control

Every batch of Difluoro-Propanedioicacid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept sealed under dry, inert conditions to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.