Description

Diethyl 3-Trifluoromethylphenyl Malonate is a high-purity fluorinated malonate ester, a critical building block in advanced organic synthesis. This compound is valued for its trifluoromethylphenyl group, which imparts unique electronic and steric properties to target molecules, enhancing their metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethylphenyl moiety for enhanced bioactivity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine group improves environmental stability and efficacy.
• Material Science Precursor: Serves as a monomer or modifier in the development of specialty polymers and coatings with tailored surface properties.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: An essential reagent for academic and industrial research exploring the effects of fluorinated aromatics in molecular design.
• Fine Chemical Production: Utilized in multi-step syntheses of complex dyes, flavors, and fragrances.

Basic Information

Product Name	Diethyl 3-Trifluoromethylphenyl Malonate
CAS No.	1997-28-0
Molecular Formula	C₁₄H₁₅F₃O₄
Molecular Weight	304.26 g/mol
Synonyms	Diethyl (3-(trifluoromethyl)phenyl)malonate; Diethyl 3-(Trifluoromethyl)phenylmalonate; Propanedioic acid, 2-[3-(trifluoromethyl)phenyl]-, 1,3-diethyl ester; 3-Trifluoromethylphenylmalonic Acid Diethyl Ester; 1,3-Diethyl 2-[3-(trifluoromethyl)phenyl]propanedioate; Diethyl (m-Trifluoromethylphenyl)malonate; m-Trifluoromethylphenylmalonic Acid Diethyl Ester; Ethyl 3-Trifluoromethylphenyl Malonate
EINECS	Contact for details

Quality Control

Our Diethyl 3-Trifluoromethylphenyl Malonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.