Description

3,3-Bis(Trifluoromethyl)-3-Hydroxypropionic Acid is a high-value fluorinated organic acid building block. This compound is prized for its unique chemical structure, which introduces significant steric bulk and electron-withdrawing trifluoromethyl groups, making it a versatile intermediate in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty materials sectors for creating novel active ingredients and performance polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those requiring fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl groups improve efficacy and environmental profile.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers, coatings, and resins with enhanced chemical resistance and thermal stability.
• Ligand and Catalyst Design: Employed in organometallic chemistry to create sophisticated ligands for catalysis, leveraging the steric and electronic properties of the bis(trifluoromethyl) group.
• Fluorine Chemistry Research: A critical reagent for academic and industrial research exploring new methodologies in fluoroorganic chemistry.
• Electronic Chemicals: Potential use in the synthesis of specialty chemicals for the electronics industry, such as etchants or precursors for thin-film deposition.

Basic Information

Item	Details
Product Name	3,3-Bis(Trifluoromethyl)-3-Hydroxypropionic Acid
CAS No.	1547-36-0
Molecular Formula	C5H4F6O3
Molecular Weight	226.08 g/mol
Synonyms	3-Hydroxy-3,3-bis(trifluoromethyl)propanoic acid; 3,3-Bis(trifluoromethyl)-3-hydroxypropanoic acid; 3,3,3-Trifluoro-2-(trifluoromethyl)-2-hydroxypropionic acid; 2-Hydroxy-2-(trifluoromethyl)-4,4,4-trifluorobutanoic acid; 3-Hydroxy-3-(trifluoromethyl)-4,4,4-trifluorobutanoic acid; Perfluoro-tert-butyl glycolic acid; Pentafluoro-tert-butyl glycolic acid; 1547-36-0
EINECS	Contact for details

Quality Control

Our production of 3,3-Bis(Trifluoromethyl)-3-Hydroxypropionic Acid adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, NMR, and GC to ensure high purity and consistent lot-to-lot performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.