Description

Oxazole, 2-[[2-(Diphenylphosphino)Phenyl]Methyl]-4,5-Dihydro-4-(Phenylmethyl)-, (4S)- is a sophisticated chiral ligand and key intermediate in advanced organic synthesis. This compound matters for its role in facilitating highly selective catalytic transformations, particularly in asymmetric hydrogenation and cross-coupling reactions, which are critical for producing enantiomerically pure pharmaceuticals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-performance, specialized ligands for complex synthesis.

Application

• As a chiral ligand in asymmetric catalysis, including hydrogenation and C-C bond-forming reactions.
• As a key intermediate in the synthesis of novel, biologically active molecules for pharmaceutical research.
• For the development of transition metal catalysts used in fine chemical and agrochemical manufacturing.
• In academic and industrial R&D for exploring new catalytic methodologies and reaction pathways.
• For the scale-up production of enantiomerically enriched compounds under GMP conditions.
• As a specialty chemical in the synthesis of advanced materials and functional polymers.

Basic Information

Item	Details
Product Name	Oxazole, 2-[[2-(Diphenylphosphino)Phenyl]Methyl]-4,5-Dihydro-4-(Phenylmethyl)-, (4S)-
CAS No.	947618-05-5
Molecular Formula	C29H28NOP
Molecular Weight	437.51 g/mol
Synonyms	(4S)-2-[[2-(Diphenylphosphino)Phenyl]Methyl]-4,5-Dihydro-4-(Phenylmethyl)Oxazole; (S)-2-((2-(Diphenylphosphino)Benzyl)-4-Benzyl-4,5-Dihydrooxazole; (S)-2-((2-(Diphenylphosphino)Benzyl)-4-Benzyl-2-Oxazoline; (S)-4-Benzyl-2-((2-(Diphenylphosphino)Benzyl)-2-Oxazoline; (S)-DBFOX; (S)-DBFOX Ligand; Chiral DBFOX Ligand; (S)-2-[2-(Diphenylphosphino)Benzyl]-4-Benzyl-4,5-Dihydrooxazole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and enantiomeric excess, supporting critical research and process development. Certificates of Analysis (COA) are available upon request, detailing specifications such as assay, chiral purity, and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.